If you have yet to discover the incredible comfort and ease of the Mississippi Pot Roast Recipe, get ready for a revelation. This slow-cooked wonder brings together just a handful of simple ingredients to create a rich, flavorful roast that literally melts in your mouth. The blend of ranch seasoning, au jus mix, butter, and tangy pepperoncini peppers makes every bite a perfect balance of savory, slightly spicy, and buttery goodness. Whether you’re feeding a hungry family or looking for a show-stopping dish to impress friends, this recipe is a total game-changer in your weeknight dinner rotation.

Ingredients You’ll Need
Gathering the right ingredients is half the fun with the Mississippi Pot Roast Recipe. Each element is straightforward yet essential, working together to build the dish’s iconic deep flavor and tender texture.
- 3 pounds chuck roast: The star of the dish, chuck roast becomes wonderfully tender after slow cooking.
- 1 packet ranch dressing mix: Adds a creamy, herby punch that enhances every bite.
- 1 packet au jus mix: Provides a rich, beefy depth that complements the roast perfectly.
- 6 tablespoons butter: Ensures the roast stays moist and adds luxurious richness.
- 6-8 pepperoncini peppers: Bring a gentle heat and bright, tangy flavor that lifts the entire pot roast.
How to Make Mississippi Pot Roast Recipe
Step 1: Prepare the Slow Cooker
Start by placing your chuck roast inside a slow cooker liner for an easy cleanup and to keep all the juicy flavors locked in. This liner also helps the roast cook evenly and prevents sticking.
Step 2: Season the Roast
Sprinkle both the ranch dressing mix and the au jus mix directly over the top of the meat. These seasoning packets create an irresistible crust and infuse the roast with their combined savory and herby aromas.
Step 3: Add Butter and Peppers
Dot the roast generously with pats of butter, then layer the pepperoncini peppers on top. The butter melts slowly, basting the meat, while the peppers add a subtle zing and depth that you won’t find in any other pot roast.
Step 4: Pour the Pepperoncini Brine
Carefully pour in half a cup or more of the brine from the pepperoncini jar. This brine is a secret ingredient that tenderizes the meat even more while imparting a bright, tangy bite that balances the richness.
Step 5: Seal and Cook
If you’re prepping ahead or want to save the recipe for later, tightly close the liner now and freeze for up to three months. Otherwise, open the liner’s edges so it fits snugly inside your slow cooker and seal the top to lock in moisture.
Step 6: Slow Cook on Low
Set the slow cooker to LOW and cook the roast for 8 hours. This long, slow heat is what transforms the chuck roast into fork-tender perfection that shreds effortlessly.
Step 7: Shred and Serve
When the roast is fall-apart tender, shred it right in the pot using two forks. Stir the shredded meat into the delicious buttery sauce with tangy juices, then serve immediately for maximum flavor and comfort.
How to Serve Mississippi Pot Roast Recipe

Garnishes
A simple garnish can elevate this hearty dish. Fresh chopped parsley or chives add a touch of color and freshness that contrast nicely with the rich flavors. For a little extra zing, sprinkle some crushed red pepper flakes if you love heat.
Side Dishes
This Mississippi Pot Roast Recipe pairs beautifully with classic comfort sides like creamy mashed potatoes, buttery dinner rolls, or even roasted vegetables. The rich sauce from the roast makes an incredible gravy, so don’t be shy about serving it alongside fluffy rice or buttery egg noodles as well.
Creative Ways to Present
For a crowd-pleasing twist, pile the shredded pot roast onto slider buns for irresistible sandwiches or stuff it into soft taco shells topped with a crunchy slaw. You can even use the leftovers to make loaded baked potatoes or hearty pot roast nachos. The flavor versatility is truly endless!
Make Ahead and Storage
Storing Leftovers
Once cooled, place leftover Mississippi Pot Roast in an airtight container and refrigerate. It stays delicious for up to four days and is perfect for quick lunches or dinners.
Freezing
This recipe freezes beautifully if you want to make it in bulk. Freeze the shredded meat and sauce in freezer-safe bags or containers for up to three months. Be sure to label and date your packages for easy thawing later.
Reheating
Reheat leftovers gently in a saucepan over low heat, adding a splash of beef broth or water to loosen the sauce if needed. Alternatively, microwave in short intervals, stirring in between to warm the dish evenly while keeping that melt-in-your-mouth texture.
FAQs
Can I use a different cut of beef for Mississippi Pot Roast Recipe?
Chuck roast is preferred because of its fat content and connective tissue, which break down for tender, flavorful meat. However, you can use brisket or rump roast if needed, but the texture might differ slightly.
What if I don’t have pepperoncini peppers or brine?
Pepperoncini provide a unique tang and mild heat. If you can’t find them, you can substitute with mild pickled banana peppers and a bit of their brine, but note that the flavor will be slightly different.
Can I cook this in the oven instead of a slow cooker?
Yes! Cover the roast tightly in a Dutch oven and bake at 275°F for 3-4 hours or until tender. Just follow the same seasoning steps before placing it in the oven.
Is this recipe spicy?
The pepperoncini peppers give a mild tangy heat, but it’s not overwhelmingly spicy. If you prefer less heat, reduce the number of peppers or omit the brine.
How can I make Mississippi Pot Roast Recipe for fewer people?
Simply halve the ingredients and use a smaller cut of chuck roast. Adjust cooking times slightly based on the size of the meat to ensure it’s tender without overcooking.
Final Thoughts
There’s something magical about how a few simple pantry staples come together to create the unforgettable magic of the Mississippi Pot Roast Recipe. It’s the kind of dish that welcomes you home with warmth, ease, and incredible flavor every single time. I encourage you to give it a try—you’ll soon wonder how you ever lived without it in your recipe arsenal!
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Mississippi Pot Roast Recipe
- Prep Time: 5 minutes
- Cook Time: 8 hours
- Total Time: 8 hours 5 minutes
- Yield: 8 servings
- Category: Main Course
- Method: Slow Cooking
- Cuisine: American
Description
This Mississippi Pot Roast is a tender, flavorful slow-cooked beef dish featuring a chuck roast seasoned with ranch and au jus mixes, enriched with butter and tangy pepperoncini peppers. It’s an easy set-it-and-forget-it recipe perfect for a comforting family meal.
Ingredients
Meat
- 3 pounds chuck roast
Seasonings and Mixes
- 1 packet ranch dressing mix
- 1 packet au jus mix
Others
- 6 tablespoons butter
- 6–8 pepperoncini (pickled hot peppers)
- 1/2 cup (or more) pepperoncini brine
Instructions
- Prepare the Slow Cooker: Line your slow cooker with a slow cooker liner to make cleaning easier and prevent sticking.
- Season the Roast: Place the 3-pound chuck roast inside the liner, then evenly sprinkle the packet of ranch dressing mix and au jus mix over the top of the meat for layered flavors.
- Add Butter and Peppers: Distribute pats of butter over the seasoned roast, then arrange 6-8 whole pepperoncini peppers on top to infuse the beef with a subtle tang and mild heat.
- Add Brine and Store Optionally: Pour in about 1/2 cup or more of pepperoncini brine around the roast. At this point, you can tightly close the liner and freeze the roast for up to 3 months if you want to prepare it ahead of time.
- Set Up for Cooking: Place the liner into the slow cooker and open the liner edges to drape over the sides of the slow cooker.
- Slow Cook the Roast: Cook on LOW heat for 8 hours until the meat becomes fall-apart tender.
- Shred and Serve: Once cooked, use two forks to shred the roast directly in the sauce, then serve for a delicious, hearty meal.
Notes
- Using the liner helps keep the slow cooker clean and makes serving easier.
- You can adjust the amount of pepperoncini and brine depending on your heat and tang preference.
- Freezing the roast with the brine and seasonings in the liner allows you to prep in advance for a convenient meal later.
- The roast is best served with mashed potatoes or rice to soak up the flavorful juices.

